<p>The Seattle Seahawks (5-0) are favored by 3.5 points as they attempt to keep their five-game winning streak intact in a matchup with the Arizona Cardinals (4-2) on Sunday, October 25, 2020 at State Farm Stadium. The point total is set at 54.5.</p>
<h4>How To Watch</h4>
<p><strong>Time:</strong> 8:20 PM EST<br /><strong>TV Channel:</strong> NBC</p>
<h4>Betting Information</h4>
<table class="table">
<caption>Seahawks vs Cardinals Betting Information</caption>
<thead>
<tr>
<th scope="col">Favorite</th>
<th scope="col">Spread</th>
<th scope="col">Favorite Spread Odds</th>
<th scope="col">Underdog Spread Odds</th>
<th scope="col">Total</th>
<th scope="col">Over Total Odds</th>
<th scope="col">Under Total Odds</th>
<th scope="col">Favorite Moneyline</th>
<th scope="col">Underdog Moneyline</th>
</tr>
</thead>
<tbody>
<tr>
<td>Seahawks</td>
<td>-3.5</td>
<td>-110</td>
<td>-110</td>
<td>54.5</td>
<td>-110</td>
<td>-110</td>
<td>-190</td>
<td>160</td>
</tr>
</tbody>
</table>
<h4>Seahawks vs Cardinals: Last 5 Meetings</h4>
<p>Seattle holds an edge against Arizona over the past five meetings between these two squads, recording a 3-2 record in those games. The Seahawks and Cardinals are split 1-1 against the spread in those games. Seattle outscored Arizona 111-104 in those five head-to-head matchups.</p>
<table class="table">
<caption>Seahawks vs Cardinals: Last Five Meetings</caption>
<thead>
<tr>
<th>Date</th>
<th scope="col">Favorite</th>
<th scope="col">Home Team</th>
<th scope="col">Spread</th>
<th scope="col">Total</th>
<th scope="col">Favorite Moneyline</th>
<th scope="col">Underdog Moneyline</th>
<th scope="col">Total Yards</th>
<th scope="col">Result</th>
</tr>
</thead>
<tbody>
<tr>
<th scope="row">12/22/2019</th>
<td>Seahawks</td>
<td>Seahawks</td>
<td>-8</td>
<td>51</td>
<td>-385</td>
<td>+320</td>
<td>412-224 ARI</td>
<td>27-13 ARI</td>
</tr>
<tr>
<th scope="row">9/29/2019</th>
<td>Seahawks</td>
<td>Cardinals</td>
<td>-5.5</td>
<td>49</td>
<td>-240</td>
<td>+205</td>
<td>340-321 SEA</td>
<td>27-10 SEA</td>
</tr>
<tr>
<th scope="row">12/30/2018</th>
<td>N/A</td>
<td>Seahawks</td>
<td>N/A</td>
<td>N/A</td>
<td>N/A</td>
<td>N/A</td>
<td>291-198 SEA</td>
<td>27-24 SEA</td>
</tr>
<tr>
<th scope="row">9/30/2018</th>
<td>N/A</td>
<td>Cardinals</td>
<td>N/A</td>
<td>N/A</td>
<td>N/A</td>
<td>N/A</td>
<td>331-263 SEA</td>
<td>20-17 SEA</td>
</tr>
<tr>
<th scope="row">12/31/2017</th>
<td>N/A</td>
<td>Seahawks</td>
<td>N/A</td>
<td>N/A</td>
<td>N/A</td>
<td>N/A</td>
<td>296-259 SEA</td>
<td>26-24 ARI</td>
</tr>
</tbody>
</table>
<h4>Betting Insights: Last Three Games (Both Teams)</h4>
<ul>
<li>The Seahawks total over the last three games is 4.2 points more than the 54.5 over/under listed for this matchup.</li>
<li>Seattle has gone 3-0 against the spread and 3-0 overall over the last three contests.</li>
<li>The over has been familiar to Seattle. They have gone over the total three times in their last three games.</li>
<li>The Cardinals total over the last three games is 7.8 points fewer than the 54.5 over/under given for this matchup.</li>
<li>Arizona has been playing well lately, going 2-1 against the spread and 2-1 straight up over their last three contests.</li>
<li>Arizona has gone under the total two times in the last three contests.</li>
</ul>
<h4>Total Facts</h4>
<ul>
<li>Seahawks contests this year have an average total of 60.8, 6.3 more points than this game's over/under.</li>
<li>Cardinals contests this season have a 46.3-point average over/under, 8.2 fewer points than this game's point total.</li>
<li>Seattle's games have gone over 54.5 points three times this season 60% of matchups).</li>
<li>None of Arizona's games have gone over 54.5 points this year.</li>
<li>These two teams rack up a combined 61.5 points per game, 7.0 more points than this matchup's total.</li>
<li>Opponents of these two teams combine to average 45.7 points per game, 8.8 fewer points than this matchup's total.</li>
</ul>
<h4>Seahawks Betting Insights</h4>
<ul>
<li>Seattle has compiled a perfect 5-0 record against the spread this season.</li>
<li>Seattle's games have hit the over in all five opportunities this season.</li>
<li>This season, the Cardinals have forced an average of 1.2 turnovers per game compared to the 0.8 times Seahawks have turned the football over in each contest.</li>
<li>In games where they don't turn the football over this season, Seattle is 1-0 overall and 1-0 against the spread.</li>
<li>Arizona is 2-0 against the spread and 2-0 overall this season when they force at least 1.2 turnovers in a game.</li>
<li>Seattle's record against the spread in away games this year is 2-0, and its record on the road overall is 2-0.</li>
</ul>
<h4>Cardinals Betting Insights</h4>
<ul>
<li>Arizona has a 4-2 record against the spread.</li>
<li>The Cardinals are 2-1 ATS when playing as at least 3.5-point underdogs.</li>
<li>Most of Arizona's games this year -- five out of six -- have finished under the point total (83.3%).</li>
<li>The Cardinals have turned the ball over 1.2 times per game this season, while the Seahawks have averaged 2 takeaways per contest.</li>
<li>In games where they turn the football over 1.2 times or fewer this season, Arizona is 4-1 overall and 4-1 against the spread.</li>
<li>When they force more than 2 turnovers in a game this season, Seattle is 4-0 against the spread and 4-0 overall.</li>
<li>Arizona is an even 1-1 against the spread in home games this year, and is 1-1 overall at home.</li>
</ul>
<h4>Injury Report</h4>
<p><strong>Seahawks:</strong></p>
<p>Mike Iupati: Questionable (Back), </p>
<p>Jamal Adams: Out (Groin)
</p>
<p><strong>Cardinals:</strong></p>
<p>Dre Kirkpatrick: Questionable (Foot), </p>
<p>Kylie Fitts: Questionable (Hamstring), </p>
<p>Dennis Gardeck: Questionable (Foot), </p>
<p>Kelvin Beachum: Questionable (Ankle), </p>
<p>DeAndre Hopkins: Questionable (Ankle), </p>
<p>Jordan Phillips: Questionable (Foot)
</p>
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View NFL betting odds, lines, and player stats for the matchup between the Seattle Seahawks and the Arizona Cardinals on Sunday, 10/25/2020.

The Cardinals are a 3.5-point underdog against Russell Wilson and the Seahawks.